Which Is Better— Viagra Or Cialis?

Which Is Better— Viagra Or Cialis?

As the medical treatment for curing erectile dysfunction has taken a brisk pace— the people are looking to resort to the most effective treatment without having to invest much.

It means they are looking for maximum efficiency at minimum cost.

Over the past two decades, Viagra and Cialis have worked as an efficient crutch for supporting the erection in comparison to expensive penile surgeries.


Also ReadThe Difference between Viagra and Generic Viagra


They have built their own audience segment, and each one of them has their own preferences; however, the curiosity to find which supersedes the other has sparked a battle between the two giants.

So, let’s find out who sweeps the battle.

  • Components

Viagra uses Sildenafil Citrate as the dynamic component whereas Cialis uses Tadalafil as the active ingredient.

Both the chemicals inhibit the PDE5 enzymes— the enzyme which destroys cGMP— the neuro-messenger between the brain and the penis.

They stop the enzyme and increase the cGMP level to allow more blood inrush in the penis.

  • Bioavailability

It’s one of the most important factors to measure the efficiency of the drug.

If the bioavailability of the drug is high, it means that more drug has entered into the bloodstream after first pass metabolism (the process which barres the drug from entering the blood circulation and reduces the concentration of the medicine).

Through the oral route of administration, the bioavailability of Sildenafil-ladened Viagra is 40% whereas more than 80% of Tadalafil-rich Cialis reaches the blood.

It means that our body receives more Cialis than Viagra.

  • The onset of action

Sildenafil-based Viagra produces a first erection in 12 minutes good enough for penetration whereas the average onset time is less than 30 minutes in most of the patients. [1]

Contrary to Viagra, the Tadalafil-based Cialis reaches the maximum concentration in 2 hours; however, a lot of patients (as much as 40% of respondents) have observed its potency in less than 15 minutes. [2]

  • The rate of absorption

The impact of Sildenafil-stuffed Viagra stays up to 4 hours. Viagra is absorbed in the body much quickly. It has a short half-life because of the standard pharmacokinetic feature.

The impact of Tadalafil-crammed Cialis may last up to 36 long hours. Cialis is steadily absorbed in the body in comparison to Viagra because of its unique pharmacokinetic attribute which slows down the absorption rate. [3]

  • The impact of external diet

With fatty meal, alcohol, or grape juice, the efficacy of Viagra subdues. When a person takes Viagra with the stated elements, the rate of absorption slows down, and the rate of treatment failure increases.

As opposed to Viagra, Cialis doesn’t underperform in the presence of fatty meal, alcohol, or grapefruits. It doesn’t cross-react with any chemical, and its absorption rate remains the same— which means that Cialis can be taken with alcohol or fatty meals.

  • The risk of the more extended half-life period

Viagra or Cialis, both are contraindicated if a patient takes nitrate-based medicines; however, if the doctor prescribes either of the two, then the patient may consider it.

As viagra has a shorter half-life, the person suffering cardiovascular issues will only have to defer the nitrate medication for 24 hours.

But with Cialis and its long half-life duration, the patient on nitrate-medication will have to abstain from administering the drug for 48 hours.

Hence, delay in nitrate-medication might aggravate the existing condition.

  • The mental freedom

As Viagra is barely useful for 4 to 6 hours, the ED-hit patients don’t get enough timeframe for stimulating themselves and preparing for the sexual session. As a result, it may induce performance anxiety in them.

However, the respondents who rely on Cialis have a larger window of freedom where they can buy time to get into the sexual mood and perform.

Hence, Cialis rules out the case of performance anxiety— one of the factors which contribute to erectile dysfunction.

In my opinion, Cialis edges over Viagra; however, both the drugs have their side-effects.

Do stick to the doctor’s prescription rather than deciding it for yourself.