Sildenafil Citrate— shortly known as Sildenafil— has been revered as a potent drug for treating erectile dysfunction in men for close to three decades now.

Having encapsulated in Viagra for 30 years, Sildenafil Citrate has managed to raise the medical bar and hopes at the same time in billions of affected males.

The Pfizer held the patent of Sildenafil when they accidentally discovered it as an erectile boosting chemical while they were working on looking out for chest pain medication.

The patent expired by 2017, and it is when the medical industry observed a revolutionizing change in the therapeutic medication of impotence.

The industry got its first generic-status where companies from the different parts of the world could make the generic-copy of Vidalista 20 Viagra at affordable rates.

It meant that the people who didn’t receive any medical care against the humiliation and impact of erectile dysfunction were supposed to get it.

And the best part was— it triggered a wave of change where people started mass-reporting their Erectile Dysfunction issues without hesitation.


So, what makes Sildenafil so unique?

I’d probably say its discovery.

It was the first active compound which reasonably prolonged the erection in a matter of few minutes.

And later in the given industry, we came across other chemical components like Tadalafil, Vardenafil, Udenafil, and Avanafil.

When it gets administered in the body, a series of chemical events take place in the bloodstream and erection takes place.

In the given piece, let’s evaluate the impacts of Sildenafil on our body. We shall also unearth how it treats erectile dysfunction in different manners.


It is what our blood vessels need.

Humans don’t respect their bodies, and that’s reasonably visible by the way they treat their blood vessels.

There’s a saying— “A person’s age gets determined by the age and the fitness of the blood vessels.”

But the saying seems to drain into the gutter because we are trying hard to block these critical carriers.

We intake bad diet, we smoke, and at worse, we also let the plaque develop in these tubes which essentially carry all the nutrients and blood.

We let these vessels to get detrimental to such a level where we deteriorate the nerves and arteries of our penis.

As our penis can’t get their share of blood supply, we cry erectile dysfunction.

The problem is with us, and not with the penis.

We are programmed to eat junk and avoid exercise (which should have been otherwise).

But, generic Sildenafil tries to undo all the mistakes without even charging a dollar.

The chemical enters into the blood circulation, relaxes the muscle walls of the blood vessels, and dilate them.

With the widening of the blood vessels, our penis receives the amount of blood which it should have received during ED for erection.


It holds the cGMP together at its hard time.

As if enhancing the action of blood vessels were not enough, Sildenafil comes up with yet another useful measure.

Our bodies have a special type of nucleotide— cGMP (Cyclic guanosine monophosphate).

cGMP is a type of messenger which carries vital information between the brain and the penis.

For example, if the penis receives the sexual stimulation, these neurotransmitters relay the message to the brain, and in response brings the erection.

But our body also has PDE5 (Phosphodiesterase 5)— an enzyme which breakdowns these messengers and hampers their message relaying properties.

Sildenafil blocks these enzymes which automatically prevents the breakdown of cGMP.

As the cGMP condition improves, the overall condition interaction between the brain and the penis gets restored which again helps in maintaining the persistent erection.

The presence of cGMP has also shown an impressive-potency in relaxing the muscle walls of the blood vessels for conducting more blood in the genitals.


What are the two ways sildenafil improves erectile dysfunction?

Sildenafil primarily improves ED by enhancing blood flow to the penis and promoting the firmness of erections.

How long does the effect of sildenafil last?

The effects of sildenafil can last up to four to six hours, providing a window for sexual activity.

Do I need sexual stimulation for sildenafil to work?

Yes, sexual stimulation is necessary for sildenafil to be effective.

Are there any side effects of sildenafil?

Common side effects may include headache, flushing, indigestion, and nasal congestion. Serious side effects are rare but possible.

Can sildenafil be used for conditions other than erectile dysfunction?

Sildenafil is also used to treat pulmonary arterial hypertension (PAH).