Natdac 60 mg

In stock
SKU
HPT5
Manufacturer
Natco Pharma
Generic Brands
Daclatasvir
Equivalent Brands
Daklinza
Strength
60mg
PharmaceuticalForm
Tablet/s
Description

Natdac 60 mg is a tablet composition of Daclatasvir which is an antiviral medicine that prevents hepatitis C virus (HCV) from multiplying in your body.

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Natdac 60 mg

Description Of Natdac 60 mg

Natdac 60 mg is a tablet composition of Daclatasvir which is an antiviral medicine that prevents hepatitis C virus (HCV) from multiplying in your body.

Improving our business planning according to market demand, we are occupied as manufacturer, supplier, distributor and exporter of a sufficient stock of Natdac 60 Daclatasvir Dihydrochloride Tablets 60mg.

Natdac 60 mg Chemical Name

  • Daclatasvir

Natdac 60 mg Manufacturer

  • Natco Pharma Ltd

Uses of Natdac 60 mg

Natdac 60 mg Tablet is used in the treatment of chronic hepatitis C virus (HCV) infection.

What is Natdac 60 mg?

Natdac (daclatasvir) is an antiviral medicine that prevents hepatitis C virus (HCV) from multiplying in your body. Natdac is used to treat genotype 1 and genotype 3 chronic hepatitis C in adults with or without cirrhosis. Natdac is given together with another drug called sofosbuvir.

How Natdac 60 mg working

Natdac tablets 60mg contain daclatasvir, a direct-acting antiviral agent that is used to treat chronic HCV infection, in combination with sofosbuvir another antiviral medication.  Daclatasvir in Natdac 60 inhibits the viral specific NS5A protein, which has no enzymatic activity but is essential for HCV RNA replication and post-replication assembly of the virus particle (virion).

It is highly effective at very low doses.  Sofosbuvir that is used in combination with Natdac 60 targets a different stage in the viral replication cycle.  It is a direct-acting nucleotide analogue inhibitor that blocks the action of the HCV NS5B polymerase, an enzyme that is essential to viral replication, by being incorporated into HCV RNA by the action of NS5B polymerase, which causes chain termination of viral RNA synthesis thereby inhibiting viral replication.

Daclatasvir in Natdac 60 works together with sofosbuvir to lower the amount of hepatitis C virus in the blood and may also lead to a cure of HCV infection over a number of weeks.  Ribavirin is a synthetic ribonucleic analogue and is incorporated into viral RNA blocking RNA synthesis; however, it does not have any antiviral activity when used alone.  This antiviral drug is used in triple combination therapy with daclatasvir in Natdac 60 and sofosbuvir in those with liver cirrhosis.

How is Natdac 60 mg used?

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it.

Natdac 60 mg Indications

The dosage should be determined by the doctor based on your age, overall medical history and current condition. The usual dose in adults for treating chronic hepatitis C is 60 mg, taken orally once daily for a period of 12 weeks.

Natdac 60 mg Dosage

If you miss a dose of Natdac 60 take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

Contraindication Of Natdac 60 mg

Drugs that cause a serious reaction with Natdac 60: the antiarrhythmic amiodarone can cause severe bradycardia (slow heartbeat).

Drugs that affect Natdac 60: anticonvulsants like carbamazepine and phenytoin, the antibacterial rifampicin, some antivirals for HIV like atazanavir, St. John’s wort.

Drugs that are affected by Natdac 60: digoxin for heart failure, rosuvastatin for high cholesterol.

Adverse effects Of Natdac 60 mg

  • headache,
  • skin rash,
  • nausea,
  • fatigue and
  • joint pain.

Special Precautions And Related Warnings Of Natdac 60 mg

You should not use Natdac 60 if you:

  • are allergic to daclatasvir or any ingredients in Natdac 60.
  • are allergic to sofosbuvir that is used in combination with Natdac.
  • are pregnant or are breastfeeding.
  • have kidney or liver disease other than hepatitis C.
  • have been infected with hepatitis B virus as treatment for HCV can increase replication of HBV and this should be monitored.
  • are taking medicines that interact with Natdac 60, including the antiarrhythmic amiodarone, anticonvulsants like carbamazepine and phenytoin, the antibacterial rifampicin, digoxin for heart failure, some antivirals for HIV like atazanavir, St. John’s wort, rosuvastatin for high cholesterol.

Storage Conditions for Natdac 60 mg

You should store your Natdac 60 below 25°C in a cool dry place.

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